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Question: Why does LA not function efficiently in an inflamed environment?
Answer: The molecule of local anaesthetic agent enters the neural cell through myelin sheath from interstitial fluid by a simple diffusion process. Then in the acidic environment of a neural cell, it breaks itself in its components and acts on the sodium influx gate and blocks it, thus blocking the generation of action potential, thus blocking signal conduction along the nerve cell membrane. The local anaesthesia cannot act on sodium influx gates from outside the nerve cell. It must enter the nerve cell.
Classification of third molar impaction is done to facilitate the communication between clinicians, for record keeping that may be used for audit research purposes. (more…)
The third molars are the most common teeth that are found to be impacted. This article will provide and introduction to this topic. The difference between simple and surgical extraction along with the aetiologies and frequency of third molar impaction are explained in a simple way.
The inferior alveolar nerve is also known as inferior dental nerve. It gives off a motor branch that supplies to mylohyoid muscle and anterior belly of digastric. Then it enters mandibular foramen and travels through the inferior alveolar canal. From inferior dental canal it supplies to mandibular third molar, second molar, first molar, and second premolar.
From the level of the second premolar, it moves forward as mental nerve and exits through mental foramen. The mental nerve supplies sensory nerve fibres to the chin and lower lip of that side. Within the mandible after mental foramen, it moves forward as incisive nerve and gives sensory supply to mandibular incisors and mandibular canines of that side. (more…)