Implant supported prostheses that include over-dentures, crowns and bridges are the treatment of choice in modern dentistry. They are very predictable in nature and have a track record of very successful life span serving their purpose. But, there are certain
Dental Implant failure
Effect of Diabetes on Osseointegration and Dental Implants
The tenacious hyperglycemia in diabetic people, hinder osteoblastic activity and modifies the response of parathyroid hormone that adjusts metabolism of Ca and P, decreases collagen synthesis during callus formation, induces apoptosis in lining cells of bone and increases osteoclastic activity due to untiring inflammatory response. It also stimulates deleterious effect on bone matrix and reduces growth and buildup of extracellular matrix. The subsequent result is reduced bone formation during healing.