Oral Lichen Planus

Oral Lichen Planus on left mucosa [1]


Question: What is oral lichen planus?

Answer: It is a chronic inflammatory condition that affects the skin, nails, hair, and mucous membranes, characterised by purplish, itchy, flat eruptions.


Question: How common is the condition?

Answer: It is a common condition in India. Its cases are reported more than 10 lakh per year in India. 


Question: How much time does it need for recovery?

Answer: It can last several years or remains lifelong.



Question: Is the condition treatable? 

Answer: Treatments can help manage conditions. There is no known cure present. 

 

Question: Does diagnosis require lab tests or imaging? 

Answer: Its diagnosis rarely requires lab tests or imaging. 

 

 

 

Condition Highlights 

  1. It commonly occurs for ages 35-50. 
  2. It is more common in females. 
  3. Family history may increase likelihood to occur. 

 

Assessment of oral mucosal disease

Oral mucosal lesions are common. They can be due to physiological changes or a local disease. They may also be an oral manifestation of a skin condition, an adverse drug reaction or systemic disease, for example, gastrointestinal disease. To manage an oral mucosal disease successfully one requires an accurate diagnosis.

Now the question arises, how will we get an accurate diagnosis?

The correct answer is, by a thorough assessment of oral mucosa for a lesion.

Assessment for an oral mucosal lesion involves taking a full patient history. This includes a medication history too. Next we need to perform a thorough extraoral and intraoral examination and use diagnostic investigations where appropriate. One should have a high index of suspicion for oral cancer.

To recognise oral cancer one should be familiar with the risk factors for oral cancer. You can see the “Oral Cancer” topic to know about risk factors for oral cancer. You should also thoroughly know the red flag features of oral cancer. If any 'red flag' features are present or the diagnosis is not clear or the patient has not responded to initial treatment, early referral to an appropriate specialist is required.  An oral medicine specialist is the most appropriate specialist to diagnose and manage oral mucosal disease, but may not be accessible. Therefore,  an oral surgeon, dermatologist or otorhinolaryngologist are other options.

Failure to respond to initial treatment, an unclear diagnosis or the presence of any suspicious features could indicate malignancy and warrant early referral.

‘Red flag’ features of oral mucosal disease

  1. oral ulcers that have lasted for more than 2 weeks 

  2. orals ulcers that recur

  3. nontraumatic oral ulcers in children 

  4. pigmented lesions on the oral mucosa

  5. red, white or mixed red and white lesions on the oral mucosa of unknown origin or with features of potentially malignant disease, such as: induration, ulceration with rolled margins, fixation to underlying tissues, lesions in high-risk sites (eg lateral tongue, floor of mouth)

  6. facial or oral paraesthesia

  7. persistent oral mucosal discomfort with no obvious cause 

  8. lumps or swellings, including lymphadenopathy

  9. swelling, pain or blockage of a salivary gland, suggestive of salivary gland disease 

  10. suspected allergy or adverse reaction to dental materials for example oral lichenoid lesion, dry mouth that is not adequately relieved with artificial salivary products and nonpharmacological methods and dry mouth caused by systemic disease

  11. suspected oral manifestations of systemic disease, for example, syphilis, Behçet syndrome, HIV, inflammatory bowel disease, lichen planus, pemphigoid

  12. lesions occurring in immunocompromised patients, for example, patients with neutropenia or HIV infection

Some oral mucosal diseases are associated with significant morbidity and mortality, particularly oral potentially malignant disorders and oral cancer. Oral potentially malignant disorders include:

  1. oral leukoplakia 
  2. oral erythroplakia
  3. chronic hyperplastic candidiasis 
  4. actinic cheilitis
  5. oral lichen planus
  6. oral submucous fibrosis
  7. discoid lupus erythematosus 
  8. dyskeratosis congenita 
  9. epidermolysis bullosa

Oral potentially malignant disorders can become malignant at the site of the lesion, but also predict an increased risk of cancer at other sites in the mouth, even in clinically normal appearing oral mucosa.

The following conditions can be managed in general practice, provided there are no 'red flag' features present that would warrant referral:

  1. recurrent aphthous ulcerative disease

  2. traumatic oral ulcers

  3. oral candidiasis

  4. angular cheilitis

  5. oral mucocutaneous herpes simplex virus

  6. dry mouth

  7. oral mucositis

  8. amalgam tattoo

  9. geographic tongue

  10.  hairy tongue.

There are physiological causes of oral mucosal discolorations, for example, Fordyce spots which are ectopic sebaceous glands and leukoedema, that do not require active management.

 

Ref:

Therapeutic guidelines (oral & dental) 2019



Acute suppurative sialadenitis

Acute suppurative sialadenitis (including parotitis) is usually caused by Staphylococcus aureus. But sometimes it may be polymicrobial in adults. In acute suppurative sialadenitis, the glands are enlarged, often hot and tense, and pus may be expressed from the Stensen's duct. The patient is usually systemically unwell, dehydrated and has difficulty swallowing.

Intraoral view of purulence emanating from the parotid duct orifice in a patient with acute suppurative parotitis [1]. 


Management


Management of acute suppurative sialadenitis includes 
  • urgent referral to hospital for surgical review
  • rehydration 
  • culture and susceptibility testing of blood samples if the swelling is fluctuant, intraductal or surgical drainage; send pus for culture and susceptibility testing 
  • antibiotic therapy, given intravenously initially then orally once the patient can swallow. 

If S. aureus is identified in a blood culture, treat as S. aureus bacteraemia. If the results of blood culture indicate a polymicrobial bacteraemia, take expert advice. 


Intravenous antibiotic therapy for acute suppurative sialadenitis 


Initiate empirical antibiotic therapy for acute suppurative sialadenitis in conjunction with local intervention or drainage. Use flucloxacillin 2 g (in case of child: 50 mg/kg up to 2 g) intravenously, 6-hourly; afterwards you can switch to oral therapy once the patient can swallow.

For patients with risk factors for methicillin-resistant Staphylococcus aureus (MRSA) infection use vancomycin intravenously (for doses see details in iridium course); switch to oral therapy once the patient can swallow.

In some regions, based on local community acquired–MRSA susceptibility patterns, clindamycin or lincomycin is a suitable alternative to vancomycin.
  • clindamycin 600 mg (child: 15 mg/kg up to 600 mg) intravenously, 8-hourly; switch to oral therapy once the patient can swallow OR
  • lincomycin 600 mg (child: 15 mg/kg up to 600 mg) intravenously, 8-hourly; switch to oral therapy once the patient can swallow.

For patients with immediate nonsevere or delayed nonsevere hypersensitivity to penicillins and without risk factors for MRSA, use cefazolin 2 g (child: 50 mg/kg up to 2 g) intravenously, 8-hourly; switch to oral therapy once the patient can swallow.
 
For patients with immediate severe or delayed severe hypersensitivity to penicillins and without risk factors for MRSA, use clindamycin or lincomycin as above.


Oral continuation therapy for acute suppurative sialadenitis 



Initiate oral continuation therapy once the patient can swallow. If the results of culture and susceptibility
testing are available, modify oral therapy accordingly. If the results of susceptibility testing are not
available, use dicloxacillin 500 mg (child: 12.5 mg/kg up to 500 mg) orally, 6-hourly for a total of 10 days (oral & intravenous) or flucloxacillin 500 mg (child: 12.5 mg/kg up to 500 mg) orally, 6-hourly for a total of 10 days (intravenous plus oral).

For patients with risk factors for methicillin-resistant Staphylococcus aureus (MRSA) infection for whom results of susceptibility testing are not available, use trimethoprim+sulfamethoxazole 160+800 mg (child 1 month or older: 4+20 mg/kg up to 160+800 mg) orally, 12-hourly for a total of 10 days (intravenous plus oral) OR clindamycin 450 mg (child: 10 mg/kg up to 450 mg) orally, 8-hourly for a total of 10 days (intravenous plus oral)*

For patients with immediate nonsevere or delayed nonsevere hypersensitivity to penicillins and without risk factors for MRSA, use
cefalexin 500 mg (child: 12.5 mg/kg up to 500 mg) orally, 6-hourly.

For patients with immediate severe or delayed severe hypersensitivity to penicillins and without risk factors for MRSA, use trimethoprim+sulfamethoxazole or clindamycin as above.

*An oral liquid formulation of clindamycin is not commercially available; for formulation options for children or people with swallowing difficulties, see the Don’t Rush to Crush Handbook, published by the Society of Hospital Pharmacists of Australia.

Ref: 
  1. HealthJade
  2. Therapeutic Guidelines Australia 2019



Dental Burs

Diamond burs are generally used for reducing tooth structures to prepare cavities for restorations or place crowns or porcelain veneers. Diamonds may also be used to smooth, refine, and polish composite or porcelain material.

Tooth Whitening

Photograph showing before and and after teeth whitening procedure. 

Tooth whitening is done to correct the discoloration of a tooth. When we talk about discoloration of a tooth, we mean to say that  the color of a tooth has changed from its normal white color to  light yellow,  yellow,  light brown to dark brown  or from light grey to dark grey or  to complete black. The discolouration may be of one tooth or all the teeth may be discoloured. Discoloration of a tooth is caused by several factors. It may be due to deposition of external stains over the surfaces of a tooth or it may be because of the internal position of certain chemicals into the teeth structure at molecular level during the period when teeth were being formed in the mother’s womb.

Composites: Composition

Composites are tooth coloured restorative materials that are usually recommended for class III, IV and class I cavities with less or no occlusal stress and esthetics are important. Specially designed composites are used in almost 50% of class II restorations, although less durable in comparison to dental amalgam. Composites can be classified as microfilled, nanofilled, flowable, packable, all purpose and laboratory. Composites are used for provisional restorations and core build-ups and in fibre-reinforced posts.

Composites: Properties

You have read about the composition of dental composites in earlier class notes This article will speak about the properties. 

Properties of Composites

The important properties of the composites are as follows:
  1. Polymerisation shrinkage - should be low
  2. Water sorption - should be low
  3. Coefficient of thermal expansion - should be same as tooth
  4. Fracture resistance - should be high
  5. Wear resistance - should be high
  6. Radiopacity- should be high
  7. Bond strength to enamel & dentin - should be high
  8. Colour match to tooth structure - should be excellent
  9. Manipulation - should be easy
  10. Finishing and polishing - should be easy
Few of the above mentioned properties may be important for anterior than posteriors restorations and vice versa. The properties of 
microfilled and nanofilled composites are same while the microhybrid's differ from both of them.

Direct Esthetic Restorative Materials

Direct Esthetic Restorative Materials

There are four types of direct esthetic restorative materials currently in use. They are:

  1. Composites
  2. Compomers
  3. Hybrid Ionomers
  4. Glass Ionomers

Composites are dominating the materials used for direct esthetic restorations. Glass ionomers are primarily used for restorations of cervical eroded areas. Hybrid ionomers provide better esthetics than glass ionomers. Compomers provide improved handling and fluoride release when compared with composites.

Polysulfide Impression Materials

Permlastic is a polysulfide, condensation-cured, elastomeric impression material in three viscosities


Polysulfide impression materials are flexible but do not have the major changes in dimensions during storage like agar and alginate. Furthermore, the polysulfide impression is much stronger and more resistant to tearing than agar or alginate. It can be electroformed and therefore metal dies or models, in addition to gypsum models, can be prepared. 

Non-carious loss of tooth structure

 

Types, clinical features, Causes prevention & treatment


Non-carious loss of tooth structure is a problem that is often found in senior citizens and is a cause of many complaints. It is not a new entity but has acquired more attention in recent time.

Types of tooth wear

  1. Abrasion
  2. Attrition
  3. Erosion
  4. Demastication
  5. Abfraction